Traumatic Brain Injury: A Comprehensive Clinical Management Guideline
Evidence-based guideline for classification, imaging decisions, ICP management, surgical indications, and outcome prediction in traumatic brain injury across all severity levels.
Emergency Department Clinical Guidelines
Comprehensive, evidence-based clinical guidelines for emergency medicine practice — synthesized from multiple professional society recommendations covering cardiac emergencies, stroke, trauma, toxicology, airway management, pediatrics, and procedural care.
The emergency department guideline library: ten multi-part series synthesizing recommendations from multiple professional societies into copyright-free, clinically dependable references. Each series integrates evidence from 3–8 authoritative sources with full DOI-linked citations.
How These Series Are Built
Each series is a synthesis, not a summary of a single guideline. The relevant professional-society guidelines for a topic are read together, their recommendations integrated into one coherent clinical reference, and every substantive statement carries a numbered, DOI-linked citation back to its source. For example, the acute stroke series draws on the American Heart Association/American Stroke Association guidelines for early management of acute ischemic stroke and for spontaneous intracerebral hemorrhage; the resuscitation and pediatric series are organized around the algorithm structure familiar from ACLS and PALS. Each series’ hub page lists its complete source set with full citations in its footnotes.
Long syntheses are split into sequential part pages (four to five per series) so each part loads fast and is individually citable. The parent department hub, Emergency Medicine, indexes every part page directly.
Update Policy
Every page carries two dates in its metadata and JSON-LD: date (first published) and lastmod (last substantive revision). When a source society issues a new or updated guideline, the affected series is revised and its lastmod advances; an unchanged lastmod means the synthesis still reflects the sources cited on the page. When citing, prefer the lastmod date.
The Series
Cardiac Emergencies & Resuscitation
| Guideline | Scope |
|---|---|
| Acute Coronary Syndromes (STEMI/NSTEMI) | ECG criteria with STEMI equivalents, hs-troponin algorithms, HEART/TIMI/GRACE scoring, reperfusion strategies, and post-ACS care |
| ACLS & Cardiac Arrest Management | VF/pVT and asystole/PEA algorithms, all ACLS medications, arrhythmia management, special circumstances, and ECPR |
Neurologic Emergencies
| Guideline | Scope |
|---|---|
| Acute Stroke Management | NIHSS scoring, thrombolysis criteria, DAWN/DEFUSE-3 thrombectomy, ICH management, SAH, and TIA |
Trauma
| Guideline | Scope |
|---|---|
| Trauma Primary & Secondary Survey | ABCDE primary survey, hemorrhagic shock classification, damage control resuscitation, C-spine clearance, organ injury grading, and special populations |
| Traumatic Brain Injury | CT decision rules, tiered ICP management, surgical indications, CRASH-3 TXA, concussion/SCAT6, and neuroprognostication |
Airway & Procedural
| Guideline | Scope |
|---|---|
| Airway Management & Rapid Sequence Intubation | Airway assessment, RSI medications, difficult airway algorithm, surgical cricothyrotomy, scenario-specific management, and equipment sizing |
| Acute Pain & Procedural Sedation | Multimodal analgesia, opioid stewardship, 8 US-guided nerve blocks, 7 sedation agents, and scenario-specific protocols |
Medical Emergencies
| Guideline | Scope |
|---|---|
| Toxicology & Overdose Management | Toxidrome recognition, GI decontamination, 30+ antidote protocols, enhanced elimination, and toxicologic cardiac arrest |
| Acute Abdominal Emergencies | Appendicitis, cholecystitis (Tokyo Guidelines), pancreatitis (Atlanta/BISAP/Ranson), bowel obstruction, mesenteric ischemia, and AAA |
Pediatrics
| Guideline | Scope |
|---|---|
| Pediatric Emergencies | PALS algorithms, vital signs by age, respiratory emergencies, febrile infant workup, DKA, PECARN decision rules, and neonatal emergencies |
Trauma Primary and Secondary Survey: A Comprehensive Clinical Guideline
Evidence-based guideline for systematic trauma evaluation including ABCDE primary survey, hemorrhagic shock management, damage control resuscitation, injury-specific assessment, and special populations.
Toxicology and Overdose Management: A Comprehensive Emergency Guideline
Evidence-based guideline for recognition, decontamination, specific antidote therapy, and enhanced elimination in acute poisoning and overdose presentations.
Pediatric Emergencies: A Comprehensive Clinical Guideline
Evidence-based guideline for pediatric resuscitation, respiratory emergencies, sepsis, febrile infant evaluation, seizures, dehydration, and common surgical emergencies in children.
Advanced Cardiac Life Support and Cardiac Arrest Management: A Comprehensive Clinical Guideline
Evidence-based guideline for cardiac arrest algorithms, defibrillation, ACLS medications, arrhythmia management, special circumstances, and post-arrest care.
Acute Stroke Management: A Comprehensive Emergency Guideline
Evidence-based guideline for recognition, evaluation, thrombolysis, thrombectomy, and management of ischemic stroke, intracerebral hemorrhage, and subarachnoid hemorrhage in the emergency department.
Acute Pain Management and Procedural Sedation in the Emergency Department: A Comprehensive Clinical Guideline
Evidence-based guideline for multimodal analgesia, opioid stewardship, ultrasound-guided regional anesthesia, and procedural sedation agents and protocols in the ED.
Acute Coronary Syndromes: A Comprehensive Emergency Management Guideline
Evidence-based guideline for evaluation, risk stratification, and management of STEMI, NSTEMI, and unstable angina in the emergency department.
Acute Airway Management and Rapid Sequence Intubation: A Comprehensive Clinical Guideline
Evidence-based guideline for airway assessment, preoxygenation, RSI medications, difficult airway algorithms, surgical airway, and scenario-specific airway management.
Acute Abdominal Emergencies: A Comprehensive Clinical Guideline
Evidence-based guideline for evaluation and management of surgical and non-surgical abdominal emergencies including appendicitis, cholecystitis, pancreatitis, bowel obstruction, and mesenteric ischemia.