Trauma Primary and Secondary Survey: A Comprehensive Clinical Guideline

Evidence-based guideline for systematic trauma evaluation including ABCDE primary survey, hemorrhagic shock management, damage control resuscitation, injury-specific assessment, and special populations.

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5
Last revised
March 2026
Editorial responsibility
The Clinical Database

A comprehensive, evidence-based clinical guideline for the systematic evaluation and initial management of adult and pediatric trauma patients, encompassing trauma team activation, the ABCDE primary survey, adjuncts to primary survey, secondary survey with head-to-toe examination, hemorrhagic shock classification and management, damage control resuscitation, injury-specific focused assessment, and special trauma populations. This resource synthesizes recommendations from the major international trauma surgery and emergency medicine professional societies, national trauma quality programs, injury scaling committees, and critical care consensus groups into a single integrated reference for emergency physicians, trauma surgeons, intensivists, anesthesiologists, and advanced practice providers who manage injured patients.1 2 3 4 5 6 7 8

Trauma remains the leading cause of death for individuals aged 1 to 44 years and accounts for approximately 4.4 million deaths worldwide annually. In the United States, injury-related deaths exceeded 278,000 in 2022, with motor vehicle crashes, falls, and firearms representing the leading mechanisms. The structured approach to trauma evaluation – a rapid, reproducible primary survey identifying and treating immediately life-threatening conditions, followed by a thorough secondary survey – has been the international standard of care since the 1970s and is credited with significant reductions in preventable trauma mortality. Damage control resuscitation, balanced transfusion strategies, and selective nonoperative management of solid organ injuries represent major paradigm shifts of the past two decades that are now firmly embedded in contemporary trauma care.


Contents:

PartTitleCoverage
Part 1Trauma Team Activation & Primary Survey (ABCDE)Two-tier trauma team activation criteria; CDC field triage decision scheme; Airway with C-spine protection (jaw thrust, oropharyngeal/nasopharyngeal airways, definitive airway indications, RSI cross-reference, cricothyrotomy technique); Breathing (tension pneumothorax, open pneumothorax, massive hemothorax, flail chest); Circulation with hemorrhage control (direct pressure, tourniquets, pelvic binder, permissive hypotension, massive transfusion protocol, FAST exam, REBOA); Disability (complete 15-point GCS scoring table, pupil assessment, lateralizing signs); Exposure/Environment
Part 2Adjuncts to Primary Survey, Secondary Survey & Hemorrhagic ShockFAST and eFAST (technique and interpretation); chest and pelvis radiography; Foley catheter; NG/OG tube; secondary survey head-to-toe examination; AMPLE history; hemorrhagic shock classification (Classes I-IV complete table); physiologic response to hemorrhage
Part 3Damage Control Resuscitation & TransfusionPermissive hypotension (targets, TBI exception); massive transfusion protocol (1:1:1 ratio, activation criteria); tranexamic acid (CRASH-2 protocol); crystalloid limitation; hypothermia prevention (lethal triad); acidosis correction; calcium supplementation; viscoelastic hemostatic assays (TEG/ROTEM); whole blood resuscitation
Part 4Focused Injury-Specific AssessmentHead injury (scalp lacerations, basilar skull fracture signs, CSF leak); C-spine clearance (Canadian C-Spine Rule, NEXUS criteria, clearance algorithm); Chest (rib fractures, pulmonary contusion, aortic injury, cardiac contusion); Abdomen (FAST, CT, DPL, AAST solid organ injury grading for liver, spleen, kidney); Pelvis (stability, binder, embolization); Extremities (vascular injury hard/soft signs, compartment syndrome, fracture priorities); Spine (TLICS scoring, neurologic exam, steroid controversy)
Part 5Special Trauma PopulationsPediatric trauma (vital signs by age, Broselow, injury patterns, non-accidental trauma screening); Geriatric trauma (anticoagulant reversal, lower activation thresholds, occult shock); Pregnant trauma (physiologic changes, fetal monitoring, perimortem cesarean delivery, Rh testing); Burns (Parkland formula, rule of nines, inhalation injury, escharotomy); Penetrating vs blunt (selective non-operative management criteria)


  1. American College of Surgeons Committee on Trauma. Advanced Trauma Life Support (ATLS) Student Course Manual, 10th ed. Chicago: American College of Surgeons; 2018. URL: https://www.facs.org/quality-programs/trauma/atls/ ↩︎

  2. Galvagno SM Jr, Nahmias JT, Young DA. “Advanced Trauma Life Support Update 2019: Management and Applications for Adults and Special Populations.” Anesthesiol Clin. 2019;37(1):13-32. DOI: 10.1016/j.anclin.2018.09.001 ↩︎

  3. National Institute for Health and Care Excellence. “Major Trauma: Assessment and Initial Management (NG39).” London: NICE; 2016 (updated 2023). URL: https://www.nice.org.uk/guidance/ng39 ↩︎

  4. Cannon JW, Khan MA, Raja AS, et al. “Damage Control Resuscitation in Patients with Severe Traumatic Hemorrhage: A Practice Management Guideline from the Eastern Association for the Surgery of Trauma.” J Trauma Acute Care Surg. 2017;82(3):605-617. DOI: 10.1097/TA.0000000000001333 ↩︎

  5. Sauaia A, Moore FA, Moore EE. “Postinjury Inflammation and Organ Dysfunction.” Crit Care Clin. 2017;33(1):167-191. DOI: 10.1016/j.ccc.2016.08.006 ↩︎

  6. Mock C, Lormand JD, Goosen J, Joshipura M, Peden M. Guidelines for Essential Trauma Care. Geneva: World Health Organization; 2004. URL: https://www.who.int/publications/i/item/guidelines-for-essential-trauma-care ↩︎

  7. Holcomb JB, Tilley BC, Baraniuk S, et al. “Transfusion of Plasma, Platelets, and Red Blood Cells in a 1:1:1 vs a 1:1:2 Ratio and Mortality in Patients with Severe Trauma: The PROPPR Randomized Clinical Trial.” JAMA. 2015;313(5):471-482. DOI: 10.1001/jama.2015.12 ↩︎

  8. CRASH-2 trial collaborators. “Effects of Tranexamic Acid on Death, Vascular Occlusive Events, and Blood Transfusion in Trauma Patients with Significant Haemorrhage (CRASH-2): A Randomised, Placebo-Controlled Trial.” Lancet. 2010;376(9734):23-32. DOI: 10.1016/S0140-6736(10)60835-5 ↩︎

Frequently asked questions

What is the primary survey in trauma?
The primary survey is the rapid, reproducible ABCDE assessment that identifies and treats immediately life-threatening injuries in order: Airway with cervical spine protection, Breathing, Circulation with hemorrhage control, Disability (neurologic assessment with the Glasgow Coma Scale and pupil examination), and Exposure/Environment. It is followed by adjuncts such as the eFAST examination and then a thorough head-to-toe secondary survey. This structured approach has been the international standard since the 1970s and is credited with significant reductions in preventable trauma mortality.
What qualifies as a massive transfusion?
Massive transfusion is classically defined as replacement of the patient’s entire blood volume — approximately 10 units of packed red blood cells in a 70-kg adult — within 24 hours, or transfusion of more than 4 units of PRBCs within 1 hour with anticipated ongoing need. Massive transfusion protocols deliver balanced products at a 1:1:1 plasma:platelets:PRBC ratio; in the PROPPR trial this ratio achieved hemostasis more often and produced fewer deaths from exsanguination in the first 24 hours than a 1:1:2 ratio.
What are the classes of hemorrhagic shock?
Hemorrhage is classified into four classes by estimated blood loss: Class I up to 750 mL (up to 15% of blood volume) with minimal physiologic change; Class II 750-1,500 mL (15-30%) with tachycardia and narrowed pulse pressure; Class III 1,500-2,000 mL (30-40%) with hypotension, confusion, and the need for blood products; and Class IV over 2,000 mL (over 40%) with markedly decreased blood pressure requiring massive transfusion and emergent hemorrhage control. Individual responses vary with age, medications such as beta-blockers, and rate of hemorrhage.

Trauma Primary and Secondary Survey — Part 5: Special Trauma Populations

Pediatric trauma (vital signs by age, Broselow, non-accidental trauma), geriatric trauma (anticoagulant reversal, occult shock), pregnant trauma (physiologic changes, perimortem C-section), burns (Parkland formula, rule of nines, escharotomy), and penetrating vs blunt selective non-operative management.

Trauma Primary and Secondary Survey — Part 4: Focused Injury-Specific Assessment

Head injury assessment, cervical spine clearance (Canadian C-Spine Rule, NEXUS), chest injury evaluation, abdominal assessment with AAST organ injury grading (liver, spleen, kidney), pelvic fracture management, extremity vascular injury and compartment syndrome, and spinal injury with TLICS scoring.

Trauma Primary and Secondary Survey — Part 3: Damage Control Resuscitation & Transfusion

Permissive hypotension, massive transfusion protocol with 1:1:1 ratio, tranexamic acid (CRASH-2), crystalloid limitation, hypothermia prevention, acidosis correction, viscoelastic hemostatic assays, and whole blood resuscitation.

Trauma Primary and Secondary Survey — Part 2: Adjuncts to Primary Survey, Secondary Survey & Hemorrhagic Shock

Extended FAST technique, chest and pelvis radiography, Foley and NG tube placement, complete head-to-toe secondary survey, AMPLE history, and hemorrhagic shock classification with Classes I-IV.

Trauma Primary and Secondary Survey — Part 1: Trauma Team Activation & Primary Survey (ABCDE)

Two-tier trauma team activation criteria, CDC field triage, and complete ABCDE primary survey including airway with C-spine protection, breathing and ventilation, circulation with hemorrhage control, disability assessment with GCS, and exposure/environment.