Comprehensive, evidence-based clinical guidelines for intensive care practice — synthesized from multiple professional society recommendations covering sepsis, ventilation, sedation, infection prevention, nutrition, hemostasis, renal support, post-arrest care, and transfusion medicine.
The ICU guideline library: twelve multi-part series synthesizing recommendations from multiple professional societies into copyright-free, clinically dependable references. Each series integrates evidence from 3–8 authoritative sources with full DOI-linked citations.
Each series is a synthesis, not a summary of a single guideline. The relevant professional-society guidelines for a topic are read together, their recommendations integrated into one coherent clinical reference, and every substantive statement carries a numbered, DOI-linked citation back to its source. The sepsis series, for example, synthesizes the SCCM/ESICM Surviving Sepsis Campaign guidelines, the Sepsis-3 consensus definitions, and the IDSA position on the SEP-1 bundle; the CLABSI series draws on the CDC intravascular catheter guidelines and the SHEA/IDSA compendium. Each series’ hub page lists its complete source set in its footnotes.
Two series are deliberate exceptions: the Surviving Sepsis Campaign 2026 adult and pediatric series are structured single-source references, indexing the SCCM/ESICM 2026 guidelines recommendation by recommendation (129 adult, 61 pediatric) rather than blending them with other sources.
Long syntheses are split into sequential part pages (four to six per series) so each part loads fast and is individually citable. The parent department hub, Critical Care, indexes every part page directly.
Every page carries two dates in its metadata and JSON-LD: date (first published) and lastmod (last substantive revision). When a source society issues a new or updated guideline, the affected series is revised and its lastmod advances; an unchanged lastmod means the synthesis still reflects the sources cited on the page. When citing, prefer the lastmod date.
| Guideline | Scope |
|---|---|
| Sepsis and Septic Shock | Sepsis-3 definitions, hour-1 bundle, vasopressor dosing, empiric antimicrobials by source, corticosteroids, and organ support |
| Surviving Sepsis Campaign 2026 (Adult) | SSC/SCCM/ESICM 2026 international guidelines — 129 recommendations covering screening, antimicrobial therapy, hemodynamic management, respiratory support, adjunctive therapies, goals of care, transitions, and long-term outcomes |
| Surviving Sepsis Campaign 2026 (Children) | SSC/SCCM/ESICM 2026 pediatric guidelines — 61 recommendations covering recognition, antimicrobials, fluid therapy, vasoactives, ventilation, corticosteroids, metabolic management, ECMO, immune therapies, and long-term follow-up |
| Post-Cardiac Arrest Care & TTM | Post-ROSC management, targeted temperature management protocols, multimodal neuroprognostication, and seizure management |
| Guideline | Scope |
|---|---|
| Mechanical Ventilation & ARDS | Berlin criteria, lung-protective ventilation, ARDSNet PEEP/FiO2 tables, prone positioning, ECMO referral, and ventilator liberation |
| Ventilator-Associated Pneumonia | VAP/VAE definitions, prevention bundles, CPIS scoring, MDR-stratified empiric antibiotics, and pathogen-specific treatment |
| Guideline | Scope |
|---|---|
| Sedation, Analgesia, Delirium & Mobility (PADIS) | ABCDEF bundle, BPS/CPOT/RASS/CAM-ICU scoring, sedative dosing, delirium management, early mobility, and sleep promotion |
| Guideline | Scope |
|---|---|
| CLABSI Prevention | Insertion and maintenance bundles, CHG bathing, CRBSI diagnosis and organism-specific management, and CUSP implementation |
This series covers CLABSI in the critical care context. For CLABSI prevention program and bundle guidance outside the ICU, see the CLABSI Prevention guide tree in the Vascular Access department.
| Guideline | Scope |
|---|---|
| Nutrition in Critical Illness | NUTRIC scoring, enteral and parenteral nutrition, refeeding syndrome prevention, micronutrients, and 14 special populations |
| Guideline | Scope |
|---|---|
| VTE Prophylaxis in Critical Care | Padua/Caprini/IMPROVE scoring, pharmacologic and mechanical prophylaxis, HIT management, and special ICU populations |
| Transfusion Practice | RBC/platelet/plasma/cryo thresholds, massive transfusion protocol, TEG/ROTEM interpretation, and TRALI vs TACO |
| Guideline | Scope |
|---|---|
| Acute Kidney Injury & Renal Replacement Therapy | KDIGO staging, conservative management, CRRT prescription with citrate anticoagulation, and special populations |
Evidence-based guideline for CLABSI prevention, including insertion and maintenance bundles, supplemental strategies, diagnosis and management of catheter-related bloodstream infections, and surveillance.
Evidence-based guideline for AKI staging, prevention, conservative management, renal replacement therapy modalities, CRRT prescription, and special populations in the critically ill.