Vascular access practice in the United States is governed by a layered framework of standards, clinical practice guidelines (CPGs), and regulatory requirements. No single document covers everything — safe, defensible practice means knowing which guideline answers which question and how they fit together. This hub indexes every major vascular access guideline, summarizes what each one covers, and links to the in-depth content on this site.
How the Guidelines Fit Together
INS Infusion Therapy Standards of Practice (8th ed., 2021)
The Infusion Nurses Society (INS) Standards are the foundational reference for infusion and vascular access practice. They define device selection, insertion, site assessment, dressing and securement, flushing and locking, dwell, and documentation. The Standards establish the Vessel Health and Preservation (VHP) approach and the osmolarity/pH thresholds that drive peripheral-versus-central decisions.
See the Vascular Access pillar for the VHP framework and device-selection thresholds.
The CDC guidelines (2011, with subsequent updates) are the backbone of CLABSI prevention. They are the evidence base for the insertion and maintenance bundles standard across US hospitals.
See CLABSI Prevention: Evidence-Based Bundle Framework.
The Infectious Diseases Society of America (IDSA) guidelines define the diagnostic criteria and management pathways for catheter-related and central line-associated bloodstream infection (CRBSI/CLABSI), including when to culture, when to remove, and how to treat.
SHEA/IDSA Compendium — Strategies to Prevent CLABSI
The SHEA/IDSA Compendium translates the evidence into prioritized, practical prevention strategies for acute care, distinguishing essential practices from additional approaches for facilities with persistent rates.
MAGIC — Michigan Appropriateness Guide for Intravenous Catheters
MAGIC (Chopra et al., 2015) provides RAND/UCLA-appropriateness ratings for device selection by indication and expected duration — the most cited framework for appropriate PICC use and reducing inappropriate placements.
See Evidence-Based Device Selection.
Joint Commission NPSG 07.04.01
The Joint Commission’s National Patient Safety Goal 07.04.01 requires organizations to implement evidence-based practices to prevent CLABSI, with documented insertion and maintenance bundle adherence assessed during survey.
CMS Conditions of Participation
CMS includes HAI prevention (including CLABSI) in its Conditions of Participation, with CLABSI rates publicly reported via Hospital Compare.
AVA Clinical Practice Guidelines 2026
The Association for Vascular Access (AVA) Adult Clinical Practice Guidelines — Journal of the Association for Vascular Access (JAVA), January Supplement 2026, Volume 31 — are the most comprehensive single CPG for the field, with evidence-graded recommendations from infrastructure and patient assessment through device selection, insertion, maintenance, and complication management.
Read the full guideline summary: AVA Clinical Practice Guidelines 2026
Putting Guidelines Into Practice